In Vitro Dissolution Absorption System (IDAS)

Biopharmaceutics dissolution with better in vivo correlation

The In Vitro Dissolution Absorption System (IDASTM) combines traditional dissolution testing with a means to determine and quantify interactions with a bio-relevant membrane. IDAS provides the ability to evaluate absorption, permeation, accumulation, biomarker regulation, and metabolism, as well as the ability to test a finished dosage form from a tablet, capsule to suspension. The characterized and validated system allows for multiple dissolution media and drug products from all BCS classes

Applications:

Who benefits from IDAS™?

If you are struggling with any of the following:

  1. Independently measured solubility, permeability, and dissolution that rarely has physiologic relevance
  2. Poor correlation between in vitro drug product release characteristics and in vivo performance
  3. Limited utility of in vitro data in formulation development and optimization

IDAS1 video | IDAS2 video

Do you have issues correlating permeability and dissolution studies with in vivo studies?