IN VITRO TESTING SERVICES

Absorption Systems employs the latest technologies and methodologies in our in vitro testing.

  • Enzyme Activity Assays 
  • Molecular Biology Testing
    • Transduction Efficiency / Infectivity
    • Biodistribution & Shedding
    • Viral Shedding
  • Immunogenicity Testing
  • Biomarker and Cytokine Analysis
  • Cell-Based Assays
    • Potency GMP Lot Release Assays
    • Proliferation Bioassays using Various Cell Types
    • Cell Viability and TCID50 Titer
    • Compound Screening
  • Permeability Assay Services

    Cell-Based Absorption Systems offers different cell lines such as Caco-2, MDCK-MDR1 which are well-established tools for predicting intestinal absorption of drug candidates. Advantages of cell monolayers: Established, robust in-vitro models, […]

  • Metabolism Assay Services

    Importance of studying drug metabolism A drug candidate encounters a large variety of enzymes in the liver such as p450s and UGTs These enzymes transform the drug into active or […]

  • Physicochemical Properties and Dose Selection

    Physicochemical Property Testing Solubility Assessment (bio-buffers and formulation excipients) Dissolution Testing Chemical Stability LogD Assessment Dose Vehicle Development & Evaluation: Excipient Selection API – Compatibility Vehicle – Suitability Stability (dose […]

  • In Vitro Dissolution Absorption System (IDAS)

    Biopharmaceutics dissolution with better in vivo correlation The In Vitro Dissolution Absorption System (IDASTM) combines traditional dissolution testing with a means to determine and quantify interactions with a bio-relevant membrane. IDAS provides […]

  • In Vitro Release Testing (IVRT)

    Measurement of drug release from complex dosage forms intended for ophthalmic and topical applications is fundamental to drug product development and product equivalence testing.  Inherent to the concepts of quality […]

  • In Vitro Permeation Testing (IVPT)

    In Vitro permeation testing (IVPT) studies across biological membranes for formulations that are applied to the skin or in the eye are vital to guide product development and establish product […]