Preclinical Pharmacokinetics Testing Services

Navigating regulatory requirements for bioanalytical testing can be challenging and time-consuming. Absorption Systems’ bioanalytical experts will provide you with complete study support, from formulation to PK parameters. With the convenience of a 72-hour turnaround for plasma sample bioanalysis, you are able to make informed decisions faster with support throughout the entire process.

The Absorption Systems Difference

Complete study support from formulation to PK parameters
Rapid turnaround to support drug discovery
Experienced team with more than 30 years supporting DMPK
End-to-end in-life with bioanalytical support

FREQUENTLY ASKED QUESTIONS

What species do you work with?

Dog
Guinea Pig
Mouse
Porcine
Rabbit
Rat

Do you work with specialized animal models?

What dose routes do you use?

Routine: IV, PO, SC, IM, IP
Standard: Ophthalmic, Dermal, Intranasal, Intraoral, Buccal
Specialty: GI (ID, IJ, IC), IT, Intra-articular

What toxicity/tolerability do you measure?

CAPABILITIES

Test Articles: Small and Large Molecules, Cell & Gene Therapy
Matrices: Plasma, Tissue, Urine, Feces, Bile, Lymph, CSF
Sample Analysis and Reporting: Measured concentrations and PK parameters
72-hour turnaround time for plasma sample BA
Biofluid Sampling: Jugular vein, Portal vein, bile, cannula, urine, feces, lymph cannula (other suitable veins), CSF, Synovial Fluid, and more

TECHNOLOGIES AND METHODOLOGIES

Bertin Precellys® 24 Tissue Homogenizer
LC-HRAMS
LTQ Orbitrap
VersaMaxTM Microplate Readers
Waters ACQUITY UPLC Systems
Waters Xevo TQ Systems

Visit our online store to view protocols or purchase Express PK studies. Request a custom study design.

Online Store request a custom study design