The Effect of NaI on Stromal Loading, Distribution and Degradation of CXLO Corneal Strengthening Solution after Topical Application and UVA Exposure in New Zealand White Rabbits

The Effect of NaI on Stromal Loading, Distribution and Degradation of CXLO Corneal Strengthening Solution after Topical Application and UVA Exposure in New Zealand White Rabbits

Gum, Glenwood; Rubinfeld; Parsons, Edward
Absorption Systems, San Diego, CA; Georgetown University Medical Center, Washington, DC; Washington Hospital Center, Washington, DC; Re:Vision, Rockville MD; CXL Ophthalmics, LLC Encinitas, CA

This poster was presented at ARVO, April 2019.

The purpose of this experiment was to validate in vivo the corneal penetration and photo-stabilization of riboflavin in solution with Sodium Iodide (NaI) and to evaluate effect of NaI on the persistence of Ribostat™ (riboflavin 0.5% & sodium iodide 0.015%, CXL Ophthalmics) using recommended clinical procedures for corneal collagen cross-linking during application and UVA exposure in New Zealand White rabbits.

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