Stent Placement Studies

Study Purpose

Deployment, safety, and performance of stents placed in the coronary, peripheral or cerebral vasculature

	Type of Model Evaluation of stent placement in coronary and peripheral vessels		Time Up to two years
	Test System New Zealand White or Dutch Belted rabbits Yucatan, Yorkshire, or Gottingen pigs Beagle or Mongrel dogs Sheep

Deliverables

• Placement of intravascular stents
• Stent deployment evaluation and follow-up observations

Model Description

• Access to vessel via percutaneous method or vascular cut down
• Angiographic intra-operative evaluation
• Follow-up angiography (qualitative coronary angiography, QCA)
• Routine animal observations
• Bioanalysis/pharmacokinetics for drug-eluting stents
• IADSA & IVDSA
• Histopathology (optional)

Benefits

• Standard protocols for stent deployment
• Digital angiographic imaging
• Dedicated operations manager to facilitate study conduct and minimize turnaround time
• On-site scientists have professional experience with small and large animals
• On-site veterinarians with animal research experience
• Bioanalytical capabilities for drug-eluting stents
• Consultative assistance in animal model selection
• State-of-the-art diagnostic equipment