Establishing a Correlation Between Cornea Neovascularization and Cornea Opacity in a Suture Induce CNV Model in Rabbit

This poster was presented at ARVO, April 2019

Corneal transparency is preserved by a balance between angiogenic and antiangiogenic factors. A disruption of the aforementioned balance results in corneal neovascularization, characterized by the formation of new blood vessels growing on the cornea. Corneal neovascularization arises in diseases like pterygium, blepharitis, viral infection, mechanical or chemicals insults to cornea, contact lenses, etc and causes a significant loss in corneal transparency. We have used improved in-vivo quantification methods to establish a correlation between corneal transparency and CNV in a suture induced CNV rabbit model.