Assessment of drug gastrointestinal supersaturation using In Vitro Dissolution – Absorption System 2 (IDAS2)
Assessment of drug gastrointestinal supersaturation using In Vitro Dissolution – Absorption System 2 (IDAS2)
Yuri Bukhtiyarov, Jibin Li, Nourdine Nessah, Carlos Hidalgo, Yuehua Huang, Albert Owen and Ismael J. Hidalgo
Absorption Systems LLC
This poster was presented at AAPS PharmSci 360, November 2018
The purpose of this study was to assess an In Vitro Dissolution-Absorption System 2 (IDAS2) in pH shift mode for evaluating the effect of supersaturation of poorly soluble weakly basic drugs on their intestinal absorption.