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Knowledge Corner

>>Knowledge Corner>>

Assessment of drug gastrointestinal supersaturation using In Vitro Dissolution – Absorption System 2 (IDAS2)

Assessment of drug gastrointestinal supersaturation using In Vitro Dissolution - Absorption System 2 (IDAS2) Yuri Bukhtiyarov, Jibin Li, Nourdine Nessah, Carlos Hidalgo, Yuehua Huang, Albert Owen and Ismael [...]

2018-11-12T12:19:19+00:00November 12, 2018|Categories: In Vitro Dissolution Absorption System (IDAS)|Tags: , , |

Study of the Effect of Simulated Fast vs Fed State on the Dissolution and Permeation of BCS Class 1-4 Drugs Using the In-vitro Dissolution Absorption System 2 (IDAS2)

Study of the Effect of Simulated Fast vs Fed State on the Dissolution and Permeation of BCS Class 1-4 Drugs Using the In-vitro Dissolution Absorption System 2 (IDAS2) [...]

2018-11-12T10:06:03+00:00November 12, 2018|Categories: In Vitro Dissolution Absorption System (IDAS)|Tags: , , |

Evaluation of the In Vitro Dissolution and Absorption (IDAS2) as a potential surrogate for in vivo performance of drug formulations

Evaluation of the In Vitro Dissolution and Absorption (IDAS2) as a potential surrogate for in vivo performance of drug formulations Johayra Simithy1, Carlos Jiménez-Romero1, Geraldin Martínez1, Andrea Pravia1, Jibin [...]

Simultaneous Metabolite Profiling and CYP Induction in Plated Cryopreserved Human Hepatocytes with Omeprazole as a Model Compound

Simultaneous Metabolite Profiling and CYP Induction in Plated Cryopreserved Human Hepatocytes with Omeprazole as a Model Compound Igor Mezine, Chris Bode, Sid Bhoopathy, Albert J. Owen, and Ismael [...]

2018-11-09T15:28:50+00:00November 9, 2018|Categories: Drug Transporters|Tags: , |

Applications of the In vitro Dissolution and Absorption System 2 (IDAS2) as a Bioequivalence Biowaiver Tool

Applications of the In vitro Dissolution and Absorption System 2 (IDAS2) as a Bioequivalence Biowaiver Tool Carlos Jiménez-Romero1, Blanca M. Gálvez1, Johayra Simithy1, Geraldin Martínez1, Andrea Pravia1, Daniel Álvarez2, Pablo N. Solís2, [...]

2018-11-09T15:13:59+00:00November 9, 2018|Categories: In Vitro Dissolution Absorption System (IDAS)|Tags: , , |
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