Metabolism

Observed changes arising from metabolic drug-drug interactions can be substantial. For this reason, in vitro metabolic assessment with ExpressPlus™ screening assays plays a key role in early drug discovery as well as in advanced stages of development.

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Express and Custom In Vitro Services

In Vivo Services

Pharmacokinetics

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E-Store Features & Benefits

With our Express Assays:
Assay results shared in 5-10 business days
Report shared through the secure Absorption Systems portal
All transporter assays are CellPort Technologies® qualified
Compound requirement: 20 µL of 10 mM stock solution or pre-weighed amount (2 mg) of the test article
Easy check out and payment with credit card (Visa, Mastercard, AmEx) or Purchase Order
Data archived in 21 CFR Part 11 compliant portal for posterity
Spend more than $25,000 within a calendar year to unlock an additional 10% discount, valid for online purchases only
For additional service requests or customization, please Contact Us

Metabolism

More information on our Metabolism services

Express and Custom In Vitro Services

Express and Custom In Vitro Services

In Vivo Services

In Vivo Services

More Services

More Services

E-Store Features & Benefits

E-Store Features & Benefits

What are you looking for?

Detection of Glucuronides – Human Liver Microsomes

Metabolic Stability – Liver Microsomes

Metabolic Stability – Liver S9 Fractions

Metabolic Stability – Cyropreserved Hepatocytes

Stability with Metabolite Detection – Phase I Metabolites and Glucuronidation Liver Microsomes

CYP IC₅₀ in Human Liver Microsomes – LC-MS/MS

UGT Inhibition – Recombinant Enzymes and LC-MS/MS

Time Dependent Inhibition – IC₅₀ Shift

CYP Phenotyping – Supersomes™

CYP Inhibition IC₅₀ In Human Liver Microsomes – LC-MS/MS

CYP Phenotyping – Chemical Inhibitors

Time Dependent CYP Inhibition – IC₅₀ Shift

CYP Inhibition in Human Liver Microsomes – LC-MS/MS

Metabolism

More information on our Metabolism services

Express and Custom In Vitro Services

Express and Custom In Vitro Services

In Vivo Services

In Vivo Services

More Services

More Services

E-Store Features & Benefits

E-Store Features & Benefits

What are you looking for?

Detection of Glucuronides – Human Liver Microsomes

Metabolic Stability – Liver Microsomes

Metabolic Stability – Liver S9 Fractions

Metabolic Stability – Cyropreserved Hepatocytes

Stability with Metabolite Detection – Phase I Metabolites and Glucuronidation Liver Microsomes

CYP IC50 in Human Liver Microsomes – LC-MS/MS

UGT Inhibition – Recombinant Enzymes and LC-MS/MS

Time Dependent Inhibition – IC50 Shift

CYP Phenotyping – Supersomes™

CYP Inhibition IC50 In Human Liver Microsomes – LC-MS/MS

CYP Phenotyping – Chemical Inhibitors

Time Dependent CYP Inhibition – IC50 Shift

CYP Inhibition in Human Liver Microsomes – LC-MS/MS

CYP IC₅₀ in Human Liver Microsomes – LC-MS/MS

Time Dependent Inhibition – IC₅₀ Shift

CYP Inhibition IC₅₀ In Human Liver Microsomes – LC-MS/MS

Time Dependent CYP Inhibition – IC₅₀ Shift