E-Store

This assay is used to identify active uptake of a test compound by PepT1, using the Caco-2 cell monolayer system

EA224

This assay uses OATP1B1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OATP1B1

EA283

EA286

This assay uses MATE1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter MATE1

EA285

This assay uses OATP1B3-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OATP1B3

EA284

This assay uses OCT2-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OCT2.

EA282

This assay uses OCT1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OCT1.

EA281

This assay uses OAT3-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OAT3

EA280

This assay uses OAT1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OAT1

EA279

This assay is used to determine the interaction of a test compound with BCRP using Caco-2 cell monolayers with and without a BCRP inhibitor

EA255

This assay is used to determine the interaction of a test compound with BCRP using BCRP-MDCK cell monolayers with and without a BCRP inhibitor

EA254

This assay is used to determine the interaction of a test compound with P-gp using Caco-2 cell monolayers with and without a P-gp inhibitor.

EA253

This assay is used to determine the interaction of a test article with P-gp using MDR1- MDCK cell monolayers with and without a P-gp inhibitor

EA204