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This assay is used to identify active uptake of a test compound by PepT1, using the Caco-2 cell monolayer system
This assay uses OATP1B1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OATP1B1
This assay uses MATE1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter MATE1
This assay uses OATP1B3-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OATP1B3
This assay uses OCT2-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OCT2.
This assay uses OCT1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OCT1.
This assay uses OAT3-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OAT3
This assay uses OAT1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OAT1
This assay is used to determine the interaction of a test compound with BCRP using Caco-2 cell monolayers with and without a BCRP inhibitor
This assay is used to determine the interaction of a test compound with BCRP using BCRP-MDCK cell monolayers with and without a BCRP inhibitor
This assay is used to determine the interaction of a test compound with P-gp using Caco-2 cell monolayers with and without a P-gp inhibitor.
This assay is used to determine the interaction of a test article with P-gp using MDR1- MDCK cell monolayers with and without a P-gp inhibitor