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This assay is used to develop dose vehicle(s) for a test compound, as a solution or suspension prior to in vivo pharmacokinetic testing
This non-GLP assay is used to determine a preliminary BCS solubility classification by measuring the quasi-equilibrium solubility of a test compound in aqueous USP buffer systems at two pH values between 1.0 and 7.4
This assay is used to determine the chemical stability of a test article in buffer.
This assay is used to determine the stability of a test article in whole blood from human, rat, mouse, dog, or monkey.
This assay is used to determine the stability of a test article in plasma from human, rat, mouse, dog, or monkey.
This assay is used to determine the blood-to-plasma partition coefficient of a test compound in mice, rats, and humans in vitro
This assay uses equilibrium dialysis to determine the unbound fraction of test compound in a rat or mouse brain homogenate, a parameter that helps predict brain penetration in vivo.
Equilibrium dialysis is used in this assay to determine the percentage of test compound that binds to human, rat, dog, primate or mouse plasma proteins.
This assay is used to determine the LogD of a test article at pH 7.4 using the shake flask method.
This assay is used to determine the solubility of a test article at room temperature in aqueous buffer at pH 7.4.