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Our Express Services are optimized, screening-based protocols with deliverables securely provided in 5-10 business days. For definitive studies to support regulatory approval, or to customize our online store assays, please contact us.

Formulation Assessment

This assay is used to develop dose vehicle(s) for a test compound, as a solution or suspension prior to in vivo pharmacokinetic testing

EA982

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Preliminary BCS Solubility Classification – Shake-Flask

This non-GLP assay is used to determine a preliminary BCS solubility classification by measuring the quasi-equilibrium solubility of a test compound in aqueous USP buffer systems at two pH values between 1.0 and 7.4

EA901

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Stability In Buffer

This assay is used to determine the chemical stability of a test article in buffer.

EA154

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Whole Blood Stability

This assay is used to determine the stability of a test article in whole blood from human, rat, mouse, dog, or monkey.

EA153-J

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Plasma Stability

This assay is used to determine the stability of a test article in plasma from human, rat, mouse, dog, or monkey.

EA153-E

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Blood to Plasma Partitioning Whole Blood

This assay is used to determine the blood-to-plasma partition coefficient of a test compound in mice, rats, and humans in vitro

EA713-C

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Fraction Unbound (Rat or Mouse Brain)

This assay uses equilibrium dialysis to determine the unbound fraction of test compound in a rat or mouse brain homogenate, a parameter that helps predict brain penetration in vivo.

EA707-B

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Plasma Protein Binding in Plasma

Equilibrium dialysis is used in this assay to determine the percentage of test compound that binds to human, rat, dog, primate or mouse plasma proteins.

EA701

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LogD – Shake Flask

This assay is used to determine the LogD of a test article at pH 7.4 using the shake flask method.

EA105

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Solubility – Shake Flask

This assay is used to determine the solubility of a test article at room temperature in aqueous buffer at pH 7.4.

EA104

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