New eBook Release: Potency Assay Guide for Cell & Gene Therapy Products
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This assay is used to detect glucuronidation of a test compound after incubation with human liver microsomes in the presence of UDPGA Required from Customer Either a minimum of 1.2 […]
This assay is used to determine the metabolic stability of a test compound incubated with human, rat, dog, primate or mouse liver microsomes and to detect expected Phase I and Phase II metabolites.
This assay is used to determine the percent remaining of a test compound incubated with cryopreserved hepatocytes (mouse, rat, dog, monkey, or human).
This assay is used to determine the percent remaining of a test compound incubated with liver S9 fraction (mouse, rat, dog, monkey, or human) in the presence of cofactors.
This assay is used to determine the percent remaining of a test compound incubated with human, rat, dog, primate or mouse liver microsomes in the presence of NADPH Catalog number.
This assay is used to identify time-dependent inhibition of individual cytochrome P450 (CYP) enzymes by a test compound using the IC50 shift approach.
This assay is used to assess the potential of a test compound to inhibit individual human UDP-glucuronosyltransferase (UGT) isoforms
This assay is used to determine the IC50 for reversible inhibition of individual cytochrome P450 (CYP) enzymes by a test compound.
This assay is used to screen for reversible inhibition of individual cytochrome P450 (CYP) enzymes by a single concentration of a test compound.
This assay is used to identify time-dependent inhibition of individual cytochrome P450 (CYP) enzymes by a test compound using the IC50 shift approach.
This assay is used to identify the CYP(s) involved in the metabolism of a test compound, through the use of human liver microsomes and CYP-specific chemical inhibitors.
This assay is used to determine the potency with which a test compound inhibits cytochrome P450 (CYP) enzymes.
This assay is used to identify the CYP(s) involved in the metabolism of a test compound, through the use of CYP-specific Supersomes.