ExpressPlus P-gp IC50 Determination Using Caco-2 Cells

This P-gp transporter assay is used to determine the IC50 of a test compound for inhibition of P-gp in Caco-2 cells

Catalog number EA268

Required from Customer



Assay System

Assay Conditions

Assay QC


  1. The results from this assay are provided to the customer in the ExpressPlus report format, which may include graphical representations of data and comparison with historical data for reference compounds.
  2. The solubility of the test compound in Hanks’ buffer containing < 0.8% DMSO must be greater than the test concentration. If the solubility of the test compound is unavailable, Absorption Systems can conduct a solubility assessment at an additional charge.