ExpressPlus OAT1 IC50 Determination Using Transfected Cells

This assay is used to determine the IC50 of a test compound for inhibition of OAT1 in OAT1-transfected HEK293 cells

Catalog number EA271

Required from Customer

Deliverables

Substrate

Assay System

Assay Conditions

Assay QC

Notes

  1. The results from this assay are provided to the customer in the ExpressPlus report format, which may include graphical representations of data and comparison with historical data for reference compounds.
  2. The solubility of the test compound in Hanks’ buffer containing < 0.8% DMSO must be greater than the test concentration. If the solubility of the test compound is unavailable, Absorption Systems can conduct a solubility assessment at an additional charge.