ExpressPlus Fraction Unbound (Rat or Mouse Brain)

This assay uses equilibrium dialysis to determine the unbound fraction of test compound in a rat or mouse brain homogenate, a parameter that helps predict brain penetration in vivo

Catalog number EA707

Required from Customer



Assay System

Assay Conditions

Assay QC

Dynamic Range


  1. The results from this assay are provided to the customer in the ExpressPlus report format, which may include graphical representations of data and comparison with historical data for reference compounds.
  2. This assay uses frozen/thawed rat brain homogenate.
  3. Results from this assay, when combined with results from EA702, ExpressPlus Plasma Protein Binding (Rat Plasma) and EA203, ExpressPlus BBB Penetration Potential, may be used to predict brain permeation in vivo.