ExpressPlus Bidirectional Permeability Through Caco-2 Cell Monolayers

This assay is used to determine the permeability of a test compound through Caco-2 cell monolayers in the apical-to-basolateral and basolateral- to-apical direction

Catalog number EA202

Required from Customer

Deliverables

Substrate

Assay System

Assay Conditions

Assay QC

Notes

  1. The results from this assay are sent to the customer in the ExpressPlus report format, which may include graphical representations of data and comparison with historical data for reference compounds.
  2. This assay broadly classifies the Papp of a test compound—see EA212 for an alternative.
  3. For reproducible results the solubility of the test compound must be greater than 5 µM in HBSSg with 1% DMSO.