ExpressPlus BCRP Inhibition Assessment in BCRP-MDCK Cells

This BCRP transporter assay is used to screen for inhibition of BCRP by a test compound, by measuring its effect on the bidirectional permeability of a BCRP substrate through BCRP-MDCK cell monolayers

Catalog number EA259

Required from Customer

Deliverables

Substrate

Assay System

Assay Conditions

Assay QC

Notes

  1. The results from this assay are provided to the customer in the ExpressPlus report format, which may include graphical representations of data and comparison with historical data for reference compounds.
  2. The solubility of the test compound in Hanks’ buffer containing < 0.8% DMSO must be greater than the test concentration. If the solubility of the test compound is unavailable, Absorption Systems can conduct a solubility assessment at an additional charge.

Options

  1. The customer can request: