This assay uses OAT3-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter OAT3
6 results found for "OAT3 HEK293"
This OAT3 transporter assay is used to screen for inhibition of OAT3 by a test compound in OAT3-transfected HEK293 cells at a single concentration
This assay is used to determine the IC50 of a test compound for inhibition of OAT3 in OAT3-transfected HEK293 cells.
Intestinal Uptake Transporters, Hepatic Uptake Transporters, Renal Uptake Transporters OATP2B1, OATP1B1, OAT1 OATP1A2, OATP1B3, OAT3 PepT1, OCT1, OCT2 Uptake transporter interaction assessments are performed at Absorption Systems using various uptake […]
Why evaluate the substrate and inhibitor potential of the investigational drug for specific transporters and why do the FDA and EMA care? Membrane transporters can have clinically relevant effects on […]
OAT1 (SLC22A6) and OAT3 (SLC22A8) Transporters are validated, stable and robust cell-based assays OAT: What and Where The organic anion transporters (OATs), part of the SLC22 superfamily of transporters, are […]