This assay uses MATE1-transfected HEK293 cells to assess whether the test compound is a potential substrate of the hepatic uptake transporter MATE1
4 results found for "MATE1 HEK293"
This assay is used to screen for inhibition of MATE1 by a test compound in MATE1-transfected HEK293 cells at a single concentration.
This assay is used to determine the IC50 of a test compound for inhibition of MATE1 in MATE1-transfected HEK293 cells.
Why evaluate the substrate and inhibitor potential of the investigational drug for specific transporters and why do the FDA and EMA care? Membrane transporters can have clinically relevant effects on […]