This assay uses inside-out vesicles to assess whether the test compound is a potential substrate or inhibitor of the efflux transporter BSEP Required from Customer 50 mg of test compound […]
5 results found for "BSEP"
This BSEP transporter assay is used to screen for inhibition of BSEP by a test compound in hBSEP-expressing vesicles at a single concentration
This assay is used to determine the IC50 of a test compound for inhibition of BSEP in hBSEP-expressing vesicles.
Introduction Transporters are membrane proteins highly expressed in various organs of humans. They play a pivotal role in the absorption and disposition of both endogenous and exogenous molecules. In the […]
Why evaluate the substrate and inhibitor potential of the investigational drug for specific transporters and why do the FDA and EMA care? Membrane transporters can have clinically relevant effects on […]