5 results found for "BSEP"

BSEP Interaction Assessment in Vesicles

This assay uses inside-out vesicles to assess whether the test compound is a potential substrate or inhibitor of the efflux transporter BSEP Required from Customer 50 mg of test compound […]

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BSEP Inhibition – Vesicles

This BSEP transporter assay is used to screen for inhibition of BSEP by a test compound in hBSEP-expressing vesicles at a single concentration

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Why evaluate the substrate and inhibitor potential of the investigational drug for specific transporters and why do the FDA and EMA care? Membrane transporters can have clinically relevant effects on […]

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