This assay is used to determine the interaction of a test compound with BCRP using BCRP-MDCK cell monolayers with and without a BCRP inhibitor
7 results found for "BCRP-MDCK"
This BCRP transporter assay is used to screen for inhibition of BCRP by a test compound, by measuring its effect on the bidirectional permeability of a BCRP substrate through BCRP-MDCK cell monolayers
This assay is used to determine the IC50 of a test compound for inhibition of BCRP in BCRP-MDCK cells.
Why evaluate the substrate and inhibitor potential of the investigational drug for specific transporters and why do the FDA and EMA care? Membrane transporters can have clinically relevant effects on […]
This assay uses BCRP-transfected MDCK cells to assess whether the test compound is a potential substrate or inhibitor of the efflux transporter BCRP Required from Customer 50 mg of test […]
Cell-Based Absorption Systems offers different cell lines such as Caco-2, MDCK-MDR1 which are well-established tools for predicting intestinal absorption of drug candidates. Advantages of cell monolayers: Established, robust in-vitro models, […]
Absorption Systems is proud to announce we are now accepting requests for our CellPortReadyTM Assay Ready Plates. Assay Plates and Assay Kits are available in 12 and 24-well formats. We are […]