Ocular Therapeutics and Devices

Identify Ophthalmic Candidates to Advance into Clinical Testing

Preclinical ocular models include in vivo and ex vivo options for small and large molecules. Absorption Systems provides specialized issue-based ADME ocular tissue models that can provide a comprehensive study from design to testing to endpoint analysis using conditions optimized for your compound.
View ocular studies and assays.

Species

Mouse, Rat, Guinea Pig, Rabbit, Dog, Pig, Sheep

Dose Routes

Topical, Intracorneal, Intravitreal, Intracameral, Periocular, Punctal, Subconjunctival, Subtenon, Subchoroidal, Suprachoroidal, Subretinal

Tissues

Lids, Lacrimal Glands, Lacrimal Ducts, Conjunctiva, Sclera, Cornea, Aqueous Humor, Iris, Ciliary Body, Trabecular Meshwork, Lens, Vitreous Humor, Retina, Choroid, Optic Nerve, Adnexa

Analytical

Ocular tissue and blood samples for pharmaceuticals and biologics preclinical ocular disease models pk and permeability absorption

Ocular Structure Dose Route Tissue

 


In Vivo Ocular PK
Absorption Systems offers in vivo ocular PK studies in large and small animals, including distribution among various ocular tissues (aqueous humor, vitreous humor, retina, iris/ciliary body, etc.).

Ex Vivo Ocular Permeability
Absorption Systems offers ex vivo rabbit and human corneal tissue and rabbit conjunctival tissue permeability models with validated in vitro-in vivo correlation to predict in vivo penetration across these ocular barriers.

Ocular Equipment
Absorption Systems utilizes several pieces of state-of-the-art equipment to capture data and images for ocular studies, including optical coherence tomography (OCT).

 

Simplified with Exemplary Service
Absorption Systems provides a clear advantage with results you can trust. Research managers are dedicated to your project, acting as your personal Data Concierge™ — delivering projects on time and on budget.

How can I help?

Lisa Murray
Business Development Manager
lmurray@absorption.com
610-280-1496

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