Ex Vivo Tissue Permeability

Rugged and Validated Predefined and Custom Designed Assays

Absorption Systems' ex vivo tissue permeability service offers mechanistic models to assess drug permeability and absorption. The isolation of specific tissues eliminates interference from other physiological factors present in conventional in vivo pharmacokinetic studies. These models can be used in early-stage preclinical studies to compare different formulations of your drug or can be used post-marketing to evaluate new formulations and determine the feasibility of various dose routes.

Answer drug permeability and metabolism questions with unique, tissue-based models

Our scientists have expertise in:
• Decisions to help derive IVIVCs
• Skilled and perfected excision and preparation of tissues
• Unique models created to tackle developers' challenges

Tour the Tissue Lab

 Learn more about ex vivo tissue permeability tools and methods
 Learn more about ex vivo tissue permeability assays
 Learn more about ex vivo tissue permeability for Lead Optimization
 Learn more about ex vivo tissue permeability for NDA submissions
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Ex Vivo Tissue Permeability Assays
Unidirectional Permeability through Intestinal Tissue
Bidirectional Permeability through Intestinal Tissue
Unidirectional Permeability across Porcine Buccal Tissue
Unidirectional Permeability through Porcine Nasal Epithelium
Unidirectional Permeability through Excised Human Skin
Unidirectional Permeability through Excised Human Vaginal Tissue
Unidirectional Permeability through Excised Rabbit Vaginal Tissue
Ocular Penetration Assessment
Penetration Assessment