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Preclinical Services
- Barriers to Bioavailability
- Binding and Distribution
- Bioanalysis
- Bioavailability and Exposure
- BCS Classification
- CellPort® Drug Transporters
- Custom Services
- Dose Vehicle Assessment
- Ex Vivo Tissue Permeability
- ExpressPlus™
- Formulation Development
- In Situ Organ Perfusion
- Metabolism
- Metabolite ID and Production
- Ocular Models
- Permeability
- Physicochemical
- PK and Biodistribution
- SafetySuite™
- Toxicology
- Biologics
- Medical Devices
- Ocular
Ocular Models
Optimized ocular models focused on improving outcomes
Unique and standard preclinical ocular models to help you identify the best ocular devices or drug candidates to advance
Specialized issue based ADME ocular tissue models can provide a comprehensive study from design to testing to endpoint analysis using conditions optimized for your compound. Preclinical ocular models include in vivo, and ex vivo.
Species
Mouse, Rat, Guinea Pig, Rabbit, Dog, Pig, Sheep
Dose Routes
Topical, Intracorneal, Intravitreal, Intracameral, Periocular, Punctal, Subconjunctival, Subtenon, Subchoroidal, Suprachoroidal, Subretinal
Tissues
Lids, Lacrimal Glands, Lacrimal Ducts, Conjunctiva, Sclera, Cornea, Aqueous Humor, Iris, Ciliary Body, Trabecular Meshwork, Lens, Vitreous Humor, Retina, Choroid, Optic Nerve, Adnexa
Analytical
Ocular tissue and blood samples for pharmaceuticals and biologics preclinical ocular disease models pk and permeability absorption
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In Vivo Ocular PK |
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Ex Vivo Ocular Permeability Absorption Systems offers ex vivo rabbit and human corneal tissue and rabbit conjunctival tissue permeability models with validated in vitro-in vivo correlation to predict in vivo penetration across these ocular barriers. |
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Ocular Equipment |