Contact Us | Sitemap | Home

History & Overview

A Better Way and Why

Professional Affiliations

Job Opportunities

Bioanalytical Services

Formulation Assessment

Excretion/Toxicology

Physicochemical

CellPort Technologies™

Customer Contacts

Change My Information

Document Details

Add New Document

Products & Services

Bioanalytical Services

Formulation Assessment

Assays & Services

Biopharmaceutics Classification System (BCS)
Bioanalytical Only—develop and validate methods, collect data
Chemical Stability in different biological fluids
CYP450 Induction using human hepatocytes
CYP450 Inhibition in supersomes or microsomes
CYP450 Phenotyping
Dose Vehicle Selection
Quasi-Equilibrium Solubility
In-life Only—dose and sample non-human primates, dogs, mini-pigs and rodents
LogP, LogD Determination
Metabolic Stability determined using hepatocytes
Metabolic Stability determined using intestinal microsomes
Metabolic Stability determined using intestinal homogenates
Metabolic Stability determined using liver microsomes
Metabolic Stability determined using S9 fractions

Metabolite Identification
Permeability through Caco-2 monolayers
Permeability through MDCK monolayers
Permeability through MDR1-MDCK monolayers
Permeability through excised human buccal tissue
Permeability through excised human or rat intestinal mucosa
Permeability through rat intestine using an in situ intestinal model
P-gp Substrate and Inhibitor Determination
PK Analysis
pKa Determination
Plasma Protein Binding
Preclinical Formulation Assessment
Rat Brain Perfusion
Rat Brain-to-Plasma Ratio Determination
Red Blood Cell Partitioning
Site Specific Absorption Models —ported or cannulated bile duct, portal vein, intestinal segments in non-human primates,dogs, mini-pigs and rodents
The ADME Index™
UGT Phenotyping
UGT Inhibition

Related Literature

OS010 - Index of Assays and Services
OS011 - Specialized ADME Assessment